Bendamustine

Bortezomib

Bosutinib

Gefitinib

Nilotinib

Ofatumumab

Paclitaxel

Pazopanib

Salinomycin

Antibiotics

Hormone Suppressant

Taxanes

Retinoids

Mustards

Antibiotics

Inhibitor Drugs

Anthracycline Drugs

Platinums

Naming of Chemo Drugs

Other Drugs

Arsenic Trioxide

Brand/Trade Names: Trisenox

Formula: As₂O₃

Manufacturers:  ChemCon GmbH, ChemWerth Inc, Emcure Pharmaceuticals, Heraeus Holding

Class:

Administration: Oral

Notes:  First approved by the FDA in 2000.  Used in treatment of leukemia.

Asparaginase

Brand/Trade Names: Elspar, Kidrolase, Rylaze

Formula: C₁₃₇₇H₂₂₀₈N₃₈₂O₄₄₂S₁₇

Manufacturers: Jazz Pharmaceuticals, United Biotech Pvt Ltd

Mechanism:

Class: Enzyme

Administration: Intravenous

Notes: Breaks down amino acid asparagine in bloodstream and thereby deprives leukemia cells of supplies of this nutrient.  Also called L-asoaaginase.  Approved by the FDA in 2011.  Used in treatment of acute lymphocytic leukemia. The FDA approved asparaginase erwinia chrysanthemi (recombinant)-rywn in 2021, to help patients who have allergies to E. coli-derived asparaginase.

Eribulin

Brand/Trade Names: Halaven

Manufacturers: Eisai  Inc. Alphora Research  BrightGene Bio-Medical Technology Co.,Ltd  Eisai  Emcure Pharmaceuticals

Formula: C₄₀H₅₉NO₁₁

Mechanism: Mitotic Inhibitor

Class:

Administration: Intravenous

Notes: Approved by the FDA in 2010.  Used for treatment of breast cancer.

Calaspargase pegol-mknl

Brand/Trade Names: Asparlas

Formula:

Manufacturer: Tecoland Corporation

Mechanism: Protein conjugate

Class: Enzyme

Administration: Intravenous

Notes:  Approved by the FDA in 2018.  Used in treatment of acute lymphoblastic leukemia.

Pegaspargase

Brand/Trade Names: Oncaspar

Formula: C₁₃₇₇H₂₂₀₈N₃₈₂O₄₄₂S₁₇

Manufacturers: Tecoland Corporation, Baxalta US Inc.

Mechanism:

Class: Enzyme

Administration: Intramuscular or intravenous

Notes: Also called PEG-L-asparaginase.  Approved by the FDA in 1994.  Used in treatment of acute lymphoblastic leukemia.

Pegfilgrastim

Brand/Trade Names: Neulasta, Fulphila

Formula: C₈₄₅H₁₃₄₃N₂₂₃O₂₄₃S₉

Manufacturers: Amgen, Mylan Institutional, Coherus BioSciences Inc

Mechanism:

Class: colony-stimulating factor

Administration: Intramuscular or intravenous

Notes:  Approved by the FDA in 2015.  Not an anti-cancer drug. Given to help patient cope with loss of white blood cells.

Tazemetostat

Brand/Trade Names: Tazverik

Formula: C₃₄H₄₄N₄O₄

Manufacturer: Epizyme

Mechanism: Inhibits histone methyltransferase

Class: Enzyme inhibitor

Administration: Oral

Notes:  Approved by the FDA in 2020. Used for treatment of epithelioid sarcoma.