List of specific drug pages
Other Drugs
Arsenic Trioxide
Brand/Trade Names: Trisenox
Formula: As2O3
Manufacturers: ChemCon GmbH, ChemWerth Inc, Emcure Pharmaceuticals, Heraeus Holding
Class:
Administration: Oral
Notes: First approved by the FDA in 2000. Used in treatment of leukemia.
Asparaginase
Brand/Trade Names: Elspar, Kidrolase, Rylaze
Formula: C1377H2208N382O442S17
Manufacturers: Jazz Pharmaceuticals, United Biotech Pvt Ltd
Mechanism:
Class: Enzyme
Administration: Intravenous
Notes: Breaks down amino acid asparagine in bloodstream and thereby deprives leukemia cells of supplies of this nutrient. Also called L-asoaaginase. Approved by the FDA in 2011. Used in treatment of acute lymphocytic leukemia. The FDA approved asparaginase erwinia chrysanthemi (recombinant)-rywn in 2021, to help patients who have allergies to E. coli-derived asparaginase.
Eribulin
Brand/Trade Names: Halaven
Manufacturers: Eisai Inc. Alphora Research BrightGene Bio-Medical Technology Co.,Ltd Eisai Emcure Pharmaceuticals
Formula: C40H59NO11
Mechanism: Mitotic Inhibitor
Class:
Administration: Intravenous
Notes: Approved by the FDA in 2010. Used for treatment of breast cancer.
Calaspargase pegol-mknl
Brand/Trade Names: Asparlas
Formula:
Manufacturer: Tecoland Corporation
Mechanism: Protein conjugate
Class: Enzyme
Administration: Intravenous
Notes: Approved by the FDA in 2018. Used in treatment of acute lymphoblastic leukemia.
Pegaspargase
Brand/Trade Names: Oncaspar
Formula: C1377H2208N382O442S17
Manufacturers: Tecoland Corporation, Baxalta US Inc.
Mechanism:
Class: Enzyme
Administration: Intramuscular or intravenous
Notes: Also called PEG-L-asparaginase. Approved by the FDA in 1994. Used in treatment of acute lymphoblastic leukemia.
Pegfilgrastim
Brand/Trade Names: Neulasta, Fulphila
Formula: C845H1343N223O243S9
Manufacturers: Amgen, Mylan Institutional, Coherus BioSciences Inc
Mechanism:
Class: colony-stimulating factor
Administration: Intramuscular or intravenous
Notes: Approved by the FDA in 2015. Not an anti-cancer drug. Given to help patient cope with loss of white blood cells.
Tazemetostat
Brand/Trade Names: Tazverik
Formula: C34H44N4O4
Manufacturer: Epizyme
Mechanism: Inhibits histone methyltransferase
Class: Enzyme inhibitor
Administration: Oral
Notes: Approved by the FDA in 2020. Used for treatment of epithelioid sarcoma.
Today’s arsenal of chemotherapy agents includes many different classes of medicines. Researchers continue to find and test new drugs.