List of specific drug pages
Other Drugs
Arsenic Trioxide
Brand/Trade Names: Trisenox
Formula: As2O3
Manufacturers: ChemCon GmbH, ChemWerth Inc, Emcure Pharmaceuticals, Heraeus Holding
Class:
Administration: Oral
Notes: First approved by the FDA in 2000. Used in treatment of leukemia.
Asparaginase
Brand/Trade Names: Elspar, Kidrolase, Rylaze
Formula: C1377H2208N382O442S17
Manufacturers: Jazz Pharmaceuticals, United Biotech Pvt Ltd
Mechanism:
Class: Enzyme
Administration: Intravenous
Notes: Breaks down amino acid asparagine in bloodstream and thereby deprives leukemia cells of supplies of this nutrient. Also called L-asoaaginase. Approved by the FDA in 2011. Used in treatment of acute lymphocytic leukemia. The FDA approved asparaginase erwinia chrysanthemi (recombinant)-rywn in 2021, to help patients who have allergies to E. coli-derived asparaginase.
Eribulin
Brand/Trade Names: Halaven
Manufacturers: Eisai Inc. Alphora Research BrightGene Bio-Medical Technology Co.,Ltd Eisai Emcure Pharmaceuticals
Formula: C40H59NO11
Mechanism: Mitotic Inhibitor
Class:
Administration: Intravenous
Notes: Approved by the FDA in 2010. Used for treatment of breast cancer.
Calaspargase pegol-mknl
Brand/Trade Names: Asparlas
Formula:
Manufacturer: Tecoland Corporation
Mechanism: Protein conjugate
Class: Enzyme
Administration: Intravenous
Notes: Approved by the FDA in 2018. Used in treatment of acute lymphoblastic leukemia.
Pegaspargase
Brand/Trade Names: Oncaspar
Formula: C1377H2208N382O442S17
Manufacturers: Tecoland Corporation, Baxalta US Inc.
Mechanism:
Class: Enzyme
Administration: Intramuscular or intravenous
Notes: Also called PEG-L-asparaginase. Approved by the FDA in 1994. Used in treatment of acute lymphoblastic leukemia.
Pegfilgrastim
Brand/Trade Names: Neulasta, Fulphila
Formula: C845H1343N223O243S9
Manufacturers: Amgen, Mylan Institutional, Coherus BioSciences Inc
Mechanism:
Class: colony-stimulating factor
Administration: Intramuscular or intravenous
Notes: Approved by the FDA in 2015. Not an anti-cancer drug. Given to help patient cope with loss of white blood cells.
Tazemetostat
Brand/Trade Names: Tazverik
Formula: C34H44N4O4
Manufacturer: Epizyme
Mechanism: Inhibits histone methyltransferase
Class: Enzyme inhibitor
Administration: Oral
Notes: Approved by the FDA in 2020. Used for treatment of epithelioid sarcoma.